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Landmark NHS-wide Trial of AlcoChange DTx for Alcohol-Related Liver Disease Hits Critical Milestone
The AlcoChange NHS trial has successfully completed patient recruitment and follow-up, enrolling 324 participants across 26 NHS hospitals. This NIHR-funded, multicentre randomised controlled trial evaluated AlcoChange, a UKCA Class IIa-marked Software as a Medical Device (SaMD), for alcohol-related liver disease patients. Results expected to be published in 2026 could influence NICE guidelines and NHS digital health pathways.
Source: EIN Presswire
Read Full ArticleClinical Trial & Research
Real world implementation of AlcoChange: protocol for an individually randomised parallel group controlled trial
Published trial protocol detailing the methodology and design of the AlcoChange multicentre NHS randomised controlled trial.
Source: Trials Journal
Read PublicationAlcoChange: a digital therapeutic for patients with alcohol-related liver disease
Peer-reviewed proof-of-concept study published in JHEP Reports demonstrating the effectiveness of AlcoChange in patients with alcohol-related liver disease.
Source: JHEP Reports (Elsevier)
Read PublicationTrial of new smartphone app to help people cut drinking
Southampton CTU announces the launch of the AlcoChange clinical trial to test whether a smartphone app can help people with alcohol-related liver disease reduce their alcohol use.
Source: Southampton Clinical Trials Unit
Read MoreNIHR Funding Award – NIHR201002
Summary of the NIHR Invention for Innovation (i4i) Programme funding award that supports the multicentre AlcoChange clinical trial.
Source: NIHR Funding Awards
View AwardMedia Coverage
New app aims to help liver disease patients abstain from alcohol
A mobile phone app which helps patients with alcohol-related liver disease to stay sober could help save hundreds of lives every year.
Source: UCL News
Read ArticleNew app encourages sobriety
Royal Free London feature on AlcoChange and its use in patients with alcohol-related liver disease.
Source: Royal Free London NHS Foundation Trust
Read ArticleAlcoChange app to help alcohol-related liver disease patients stay sober
Study revealed that 57% of people using the AlcoChange app regularly remained sober across a three-month period, compared to 22% of those who did not.
Source: PharmaTimes
Read ArticleAlcoChange: a smartphone tool to reduce alcohol use and admissions
Project profile describing earlier implementation of AlcoChange to support patients with alcoholic liver disease.
Source: The Health Foundation
View ProjectAlcoChange smartphone digital therapeutic to improve outcomes in alcohol
Local research news announcing Barnsley Hospital's participation in the AlcoChange trial.
Source: Barnsley Hospital NHS Foundation Trust
Read MoreEASL "Read of the Week" – AlcoChange JHEP Reports paper
The European Association for the Study of the Liver (EASL) featured the AlcoChange JHEP Reports article as their "Read of the Week."
Source: European Association for the Study of the Liver (EASL)
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